Ketamine is composed of equivalent amounts of esketamine and arketamine. While each have therapeutic effects, esketamine compared to arketamine is a more powerful NMDA receptor and causes more dissociative effects. Besides the 1970 FDA approval for ketamine, in 2019 the FDA also authorized esketamine being used as a quick-acting antidepressant https://tomf221riw9.wikigop.com/user