These outcomes counsel that SB225002 induces p53-dependent apoptosis, and provokes mitotic catastrophe in p53-impartial fashion in p53 wild-variety cells. Reconstitution with wild-kind P53 in P53-null SKOV3 mobile attenuated SB225002-induced mitotic catastrophe, suggesting p53 prevented mitotic disaster induced by SB225002 in p53-deficient OVCA cells. Last but not least, the effect of http://abigaila863mrv5.idblogz.com/profile