At 3 times put up-MPTP, we located significant microglial activation and up-regulation of CB2 cannabinoid receptors from the ventral midbrain. Remedy with WIN or even the CB2 receptor agonist JWH015 (4 mg/kg, intraperitoneal) minimized MPTP-induced microglial activation, whereas genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. In addition, Continual https://win55.clinic/casino