There's a launch of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors from the dorsal horn to minimize afferent discomfort transmission and generate analgesia. As a result, medications like clonidine that concentrate on alpha-2 receptors can affect the transmission of discomfort. This information isn't a substitute https://baruchq516fxo1.wikicorrespondence.com/user