Limb-threatening or important limb ischemia (CLI) is manifested by Persistent (over two weeks) ischemic rest pain, ischemic wounds or tissue reduction, or gangrene in a single or both legs. Ischemic relaxation pain generally happens quickly following falling asleep; the affected person is awakened by burning discomfort or numbness in the https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/